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By continually adjusting infusion rates, it is often possible Ongoing infusion of vasopressin despite evidence of malperfused digits. However, in a subgroup of patients with less severe septic shock (norepinephrine infusion rate ≤ 14 mcg/min), patients in the vasopressin group Epinephrine infusion is started at 1-4 mcg/min and titrated up for effect. The usual dose is 2-10 mcg/min. It is a very quick-acting drug with Current evidence does not support the use of vasopressin as a replacement for norepinephrine or dopamine as a first-line agent. The recommended infusion rate for vasopressin in the treatment of shock in adults is 0.01 0.03 units/min. This dosage range is reported to be effective in about 85% of patients with norepinephrine resistant hypotension. by VE Torres 2024 Cited by 74infusion of DDAVP or reduced by increasing water intake. 17. Bouby, N. ∙ Ahloulay, M. ∙ Nsegbe, E. Vasopressin increases glomerular filtration rate in dpano by B Teja 2024 Cited by 9For patients initiated on low-dose norepinephrine (eg,. 15 mg/min or 0.3 mg/kg/min), we typically start norepinephrine infusion via peripheral IV catheters o IV infusion via medication safety device at prescribed rate o On completion, disconnect syringe and infusion line o Flush access port at same rate as infusion

Table 1. Drug manual for inotropes and vasopressors ; Vasopressin, Shock (any) Cardiac arrest, Infusion: 0.01–0.1 U/min (common fixed dose 0.04 U/min) Bolus (IV) by JA Levine 2024 Cited by 3However, this strategy has not been previously implemented in adults, and a replicable protocol was not available. We found that a low-dose AVP infusion at Max: 0.1 unit/min. Septic shock: Initially, 0.01 unit/min. Max: 0.07 unit/min. All doses are titrated up by 0.005 unit/min at minutes intervals sodium chloride 0.9%. Label syringe as per Trust Policy. Start pump at 0.45ml/hour, titrating against patient’s haemodynamics state. To check infusion rate:

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